Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5782
Gene Symbol: PTPN12
PTPN12 		0.510 Biomarker disease GENOMICS_ENGLAND Chromosomal localization of the protein tyrosine phosphatase G1 gene and characterization of the aberrant transcripts in human colon cancer cells. 7509295 1994
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.600 GeneticVariation disease UNIPROT
Entrez Id: 5782
Gene Symbol: PTPN12
PTPN12 		0.510 GeneticVariation disease UNIPROT
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.470 GeneticVariation disease UNIPROT
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.400 GeneticVariation disease UNIPROT
Entrez Id: 5795
Gene Symbol: PTPRJ
PTPRJ 		0.350 GeneticVariation disease UNIPROT
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.330 GeneticVariation disease UNIPROT
Entrez Id: 25788
Gene Symbol: RAD54B
RAD54B 		0.320 GeneticVariation disease UNIPROT
Entrez Id: 5606
Gene Symbol: MAP2K3
MAP2K3 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 894
Gene Symbol: CCND2
CCND2 		0.610 Biomarker disease RGD For example, genes involved in inflammation and matrix proteases and a cell cycle regulator gene, cyclin D2, were highly expressed in colon cancers. 15059925 2004
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.600 Biomarker disease RGD Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF. 21268133 2011
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.600 Therapeutic disease RGD High energy shock waves and 5-aminolevulinic for sonodynamic therapy: effects in a syngeneic model of colon cancer. 21214291 2011
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A 		0.520 ModifyingMutation disease RGD Identification of gene expression profiles correlated to tumor progression in a preclinical model of colon carcinogenesis. 20428773 2010
Entrez Id: 4583
Gene Symbol: MUC2
MUC2 		0.300 Biomarker disease RGD K-ras mutations and mucin profile in preneoplastic lesions and colon tumors induced in rats by 1,2-dimethylhydrazine. 17847023 2008
Entrez Id: 4583
Gene Symbol: MUC2
MUC2 		0.300 Biomarker disease RGD Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats. 20459814 2010
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.300 Biomarker disease RGD Soy isoflavones modulate azoxymethane-induced rat colon carcinogenesis exposed pre- and postnatally and inhibit growth of DLD-1 human colon adenocarcinoma cells by increasing the expression of estrogen receptor-beta. 19141699 2009
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.290 Therapeutic disease RGD PTEN regulates apoptotic cell death through PI3-K/Akt/GSK3β signaling pathway in DMH induced early colon carcinogenesis in rat. 22561258 2012
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.260 Biomarker disease RGD Chemopreventive efficacy of green tea drinking against 1,2-dimethyl hydrazine-induced rat colon carcinogenesis. 23008118 2013
Entrez Id: 79923
Gene Symbol: NANOG
NANOG 		0.260 Therapeutic disease RGD MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach. 22641368 2012
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.230 Biomarker disease RGD Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF. 21268133 2011
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		0.230 Biomarker disease RGD Using the carcinogen-induced colon cancer Sprague-Dawley rat model, we previously showed that oltipraz selectively induces NQO1 in the colons of these rats without inducing other phase II detoxifying enzymes. 19424637 2009
Entrez Id: 7033
Gene Symbol: TFF3
TFF3 		0.230 Biomarker disease RGD K-ras mutations and mucin profile in preneoplastic lesions and colon tumors induced in rats by 1,2-dimethylhydrazine. 17847023 2008
Entrez Id: 3934
Gene Symbol: LCN2
LCN2 		0.220 Therapeutic disease RGD Long-term administration of aspirin inhibits tumour formation and triggers anti-neoplastic molecular changes in a pre-clinical model of colon carcinogenesis. 20043115 2010
Entrez Id: 572
Gene Symbol: BAD
BAD 		0.220 Therapeutic disease RGD High energy shock waves and 5-aminolevulinic for sonodynamic therapy: effects in a syngeneic model of colon cancer. 21214291 2011
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		0.220 Therapeutic disease RGD Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats. 30720227 2019